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1

[Methods in Molecular Biology] Potassium Channels Volume 1684 ||

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 9.85 MB

english, 2018

2

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Site-Directed Unnatural Amino Acid Mutagenesis to Investigate Potassium Channel Pharmacology in Xenopus laevis Oocytes

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 236 KB

english, 2018

3

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Ion Binding to Transport Proteins using Isothermal Titration Calorimetry

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 378 KB

english, 2018

4

Ion Channels of the Islets in Type 2 Diabetes

Jacobson, David, Shyng, Show-Ling

Journal:

Journal of Molecular Biology

Year:

2019

Language:

english

File:

PDF, 5.02 MB

english, 2019

5

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Studying KCNQ1 Mutation and Drug Response in Type 1 Long QT Syndrome Using Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 644 KB

english, 2018

6

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Studying Structural Dynamics of Potassium Channels by Single-Molecule FRET

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 609 KB

english, 2018

7

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Nuclear Magnetic Resonance Approaches for Characterizing Protein-Protein Interactions

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 485 KB

english, 2018

8

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on β-Cell Function

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 389 KB

english, 2018

9

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Probing Subunits Interactions in KATP Channels Using Photo-Crosslinking via Genetically Encoded p-Azido-l-phenylalanine

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 277 KB

english, 2018

10

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Monitoring Changes in the Abundance of Endogenously Expressed ATP-Sensitive Potassium (KATP) Channels in the Plasma Membrane Using Surface Biotinylation

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 199 KB

english, 2018

11

[Methods in Molecular Biology] Potassium Channels Volume 1684 || In Vivo Analysis of Potassium Channelopathies: Loose Patch Recording of Purkinje Cell Firing in Living, Awake Zebrafish

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 300 KB

english, 2018

12

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Methods for Characterizing Disease-Associated ATP-Sensitive Potassium Channel Mutations

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 523 KB

english, 2018

13

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Hyper-SUMOylation of K+ Channels in Sudden Unexplained Death in Epilepsy: Isolation and Primary Culture of Dissociated Hippocampal Neurons from Newborn Mice for Subcellular Localization

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 231 KB

english, 2018

14

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Studying Kv Channels Function using Computational Methods

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 595 KB

english, 2018

15

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Migration of PIP2 on KCNQ2 Surface Revealed by Molecular Dynamics Simulations

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 805 KB

english, 2018

16

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Manipulating Potassium Channel Expression and Function in Hippocampal Neurons by In Utero Electroporation

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 120 KB

english, 2018

17

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Characterization of MC4R Regulation of the Kir7.1 Channel Using the Tl+ Flux Assay

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 437 KB

english, 2018

18

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Studying Mechanosensitivity of Two-Pore Domain K+ Channels in Cellular and Reconstituted Proteoliposome Membranes

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 408 KB

english, 2018

19

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Combinatorial Assembly of Lumitoxins

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018

20

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Random Spherically Constrained Single-Particle (RSC) Method to Study Voltage-Gated Ion Channels

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 435 KB

english, 2018

21

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Nonsense-Mediated mRNA Decay of hERG Mutations in Long QT Syndrome

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 191 KB

english, 2018

22

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Thallium Flux Assay for Measuring the Activity of Monovalent Cation Channels and Transporters

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 171 KB

english, 2018

23

[Methods in Molecular Biology] Potassium Channels Volume 1684 || Stopped-Flow Fluorometric Ion Flux Assay for Ligand-Gated Ion Channel Studies

Shyng, Show-Ling, Valiyaveetil, Francis I., Whorton, Matt

Year:

2018

Language:

english

File:

PDF, 568 KB

english, 2018

24

A Role of the Sulfonylurea Receptor 1 in Endocytic Trafficking of ATP-Sensitive Potassium Channels

Cathrin E. Bruederle, Joel Gay, Show-Ling Shyng

Journal:

Year:

2011

Language:

english

File:

PDF, 1.88 MB

english, 2011

25

Co-inheritance of two ABCC8 mutations causing an unresponsive congenital hyperinsulinism: Clinical and functional characterization of two novel ABCC8 mutations

Faletra, Flavio, Snider, Kara, Shyng, Show-Ling, Bruno, Irene, Athanasakis, Emmanouil, Gasparini, Paolo, Dionisi-Vici, Carlo, Ventura, Alessandro, Zhou, Qing, Stanley, Charles A., Burlina, Alberto

Journal:

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

26

Sulfonylurea Receptor Transmembrane Domain Zero Mutations that Disrupt Full Length and Minimal ATP-Sensitive Potassium Channel Properties

Pratt, Emily B., Tewson, Paul, Shyng, Show-Ling

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

27

Rescue and Gating of a Disease Mutation at an M2 glycine in Kir6.2 of ATP-Sensitive Potassium (KATP) Channels

Bushman, Jeremy D., Tewson, Paul H., Shyng, Show-Ling

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

28

Identification of a Heterozygous Sulfonylurea Receptor 1 Mutation that Exerts a Strong Dominant-Negative Effect on KATP Channel Response to MgADP

Zhou, Qing, Ziv, Carmit Avnon, Glaser, Benjamin, Zangen, David H., Shyng, Show-ling

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

29

Mechanism of Carbamazepine Mediated Rescue of Trafficking Defective Mutant KATP Channels

Devaraneni, Prasanna, Zhou, Qing, Olson, Erik, Shyng, Show-Ling

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 40 KB

english, 2014

30

A Glycolipid-Anchored Prion Protein Is Endocytosed via Clathrin-Coated Pits

Show-Ling Shyng, John E. Heuser and David A. Harris

Journal:

The Journal of Cell Biology

Year:

1994

Language:

english

File:

PDF, 3.99 MB

english, 1994

31

Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels

Xie, Li, Liang, Tao, Kang, Youhou, Lin, Xianguang, Sobbi, Roozbeh, Xie, Huanli, Chao, Christin, Backx, Peter, Feng, Zhong-Ping, Shyng, Show-Ling, Gaisano, Herbert Y.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

32

Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP

Zhou, Qing, Chen, Pei-Chun, Devaraneni, Prasanna K, Martin, Gregory M, Olson, Erik M, Shyng, Show-Ling

Journal:

Year:

2014

Language:

english

File:

PDF, 637 KB

english, 2014

33

Engineered Kir6.2 mutations that correct the trafficking defect of K ATP channels caused by specific SUR1 mutations

Zhou, Qing, Pratt, Emily B, Shyng, Show-Ling

Journal:

Year:

2013

Language:

english

File:

PDF, 880 KB

english, 2013

34

ATP Modulates Interaction of Syntaxin-1A with Sulfonylurea Receptor 1 to Regulate Pancreatic β-Cell K ATP Channels

Kang, Youhou, Zhang, Yi, Liang, Tao, Leung, Yuk-Man, Ng, Betty, Xie, Huanli, Chang, Nathan, Chan, Joseph, Shyng, Show-Ling, Tsushima, Robert G., Gaisano, Herbert Y.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

35

Neonatal Diabetes Caused by Mutations in Sulfonylurea Receptor 1: Interplay between Expression and Mg-Nucleotide Gating Defects of ATP-Sensitive Potassium Channels

Zhou, Qing, Garin, Intza, Castaño, Luis, Argente, Jesús, Muñoz-Calvo, Ma. Teresa, Perez de Nanclares, Guiomar, Shyng, Show-Ling

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 207 KB

english, 2010

36

Familial Leucine-Sensitive Hypoglycemia of Infancy Due to a Dominant Mutation of the β-Cell Sulfonylurea Receptor

Magge, Sheela N., Shyng, Show-Ling, MacMullen, Courtney, Steinkrauss, Linda, Ganguly, Arupa, Katz, Lorraine E. L., Stanley, Charles A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

37

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels

Martin, Gregory M., Chen, Pei-Chun, Devaraneni, Prasanna, Shyng, Show-Ling

Journal:

Frontiers in Physiology

Year:

2013

Language:

english

File:

PDF, 1.13 MB

english, 2013

38

Structurally Distinct Ligands Rescue Biogenesis Defects of the K ATP Channel Complex via a Converging Mechanism

Devaraneni, Prasanna K., Martin, Gregory M., Olson, Erik M., Zhou, Qing, Shyng, Show-Ling

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

39

Concerted Trafficking Regulation of Kv2.1 and K ATP Channels by Leptin in Pancreatic β-cells

Wu, Yi, Shyng, Show-Ling, Chen, Pei-Chun

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.69 MB

english, 2015

40

ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity

Pratt, Emily B., Shyng, Show-Ling

Journal:

Year:

2011

Language:

english

File:

PDF, 791 KB

english, 2011

41

Pharmacological Correction of Trafficking Defects in ATP-Sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations

Martin, Gregory M., Rex, Emily A., Devaraneni, Prasanna, Denton, Jerod S., Boodhansingh, Kara E., DeLeon, Diva D., Stanley, Charles A., Shyng, Show-Ling

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

42

Targeting the Gut Microbiota–FXR Signaling Axis for Glycemic Control: Does a Dietary Supplement Work Magic?

Shyng, Show-Ling

Journal:

Year:

2017

Language:

english

File:

PDF, 677 KB

english, 2017

43

NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells

Wu, Yi, Fortin, Dale A, Cochrane, Veronica A, Chen, Pei-Chun, Shyng, Show-Ling

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.46 MB

english, 2017

44

Down-Regulation of ZnT8 Expression in INS-1 Rat Pancreatic Beta Cells Reduces Insulin Content and Glucose-Inducible Insulin Secretion

Fu, Yi, Tian, Wei, Pratt, Emily B., Dirling, Lisa B., Shyng, Show-Ling, Meshul, Charles K., Cohen, David M., Maedler, Kathrin

Journal:

Year:

2009

Language:

english

File:

PDF, 393 KB

english, 2009

45

A Kir6.2 Pore Mutation Causes Inactivation of ATP-Sensitive Potassium Channels by Disrupting PIP2-Dependent Gating

Bushman, Jeremy D., Zhou, Qing, Shyng, Show-Ling, Arreola, Jorge

Journal:

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

46

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating

Martin, Gregory M, Yoshioka, Craig, Rex, Emily A, Fay, Jonathan F, Xie, Qing, Whorton, Matthew R, Chen, James Z, Shyng, Show-Ling

Journal:

Year:

2017

Language:

english

File:

PDF, 6.82 MB

english, 2017

47

Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM

Martin, Gregory M, Kandasamy, Balamurugan, DiMaio, Frank, Yoshioka, Craig, Shyng, Show-Ling

Journal:

Year:

2017

Language:

english

File:

PDF, 4.18 MB

english, 2017

48

Functional characterization of activating mutations in the SUR1 ( ABCC8 ) causing neonatal diabetes mellitus in Asian Indian children

Balamurugan, Kandasamy, Kavitha, Babu, Yang, Zhongying, Mohan, Viswanathan, Radha, Venkatesan, Shyng, Show-Ling

Journal:

Pediatric Diabetes

Year:

2019

File:

PDF, 1.60 MB

2019

49

Leptin-induced Trafficking of KATP Channels: A Mechanism to Regulate Pancreatic β-cell Excitability and Insulin Secretion

Cochrane, Veronica, Shyng, Show-Ling

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 457 KB

english, 2019

50

Pharmacological chaperones of ATP-sensitive potassium channels: Mechanistic insight from cryoEM structures

Martin, Gregory M., Sung, Min Woo, Shyng, Show-Ling

Journal:

Molecular and Cellular Endocrinology

Year:

2020

File:

PDF, 1.55 MB

2020